Ethics, policy, and legislation

Matthias Eggel, Samuel Camenzind, Paulin Jirkof. Reasons to Reduce Surplus Animals in Research (in Switzerland) – Or Why the Killing and Death of Animals and Potentially Standard Husbandry Conditions Should be Classified as Harms. LEOH - Journal of Animal Law, Ethics and One Health. 2026:1-15. doi:10.58590/leoh.2026.001

Donald E. Ingber. Challenges and opportunities for human Organ Chips in FDA assessments and pharma pipelines,. Cell Stem Cell. 2026. doi:10.1016/j.stem.2025.12.022

Sarah A Carratt, Christina L Zuch de Zafra, Elias Oziolor, et al. An industry perspective on the FDA Modernization Act 2.0/3.0: potential next steps for sponsors to reduce animal use in drug development. Toxicological Sciences. 2025;203(1):28-34. doi:10.1093/toxsci/kfae122

Pandora Pound, Rebecca Ram, Kathy Archibald. The UK’s Early Access to Medicines Scheme 10 years on: an evaluation using publicly available data. JRSM Open. 2025;16(2):20542704251317916. doi:10.1177/20542704251317916

Andrea C. del Valle. Organs on chips could make biomedical research more equitable. Nature. 2025;644(8076):338-338. doi:10.1038/d41586-025-02569-9

Surat Parvatam. India races to raise animal-free drug testing standards. Nature India. 2025. doi:10.1038/d44151-025-00151-w

Lauren Hope, Jarrod Bailey. Breaking down the barriers to animal-free research. Alternatives to Laboratory Animals. 2025;53(4):215-231. doi:10.1177/02611929251349465

Andrew S. Robertson, Nahid Latif, Imein Bousnina, et al. Accelerating adoption of new approach methodologies in regulatory decision making: an industry perspective. Nature Reviews Drug Discovery. 2025;24(6):401-402. doi:10.1038/d41573-025-00038-6

Tessel B. Wijne, Wouter P. C. Boon, Anne S. Kienhuis, Ellen H. M. Moors, Jarno Hoekman. Pursuing societal impact in research projects on NAM development: An analysis of routes to impact. NAM Journal. 2025;1:100050. doi:10.1016/j.namjnl.2025.100050

John J. Pippin, Jarrod Bailey, Mark Kennedy, et al. Institutional animal care and use committees and the challenges of evaluating animal research proposals. Research Integrity and Peer Review. 2025;10(1):11. doi:10.1186/s41073-025-00169-9