Ethics, policy, and legislation

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Simon Lohse. Reproducibility, questionable research practices and ethico-epistemic trade-offs in animal-based biomedicine. European Journal for Philosophy of Science. 2026;16(2):25. doi:10.1007/s13194-026-00727-y
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Julia Matyjasiak, Alexandra-Costina Avîrvarei, Marie Corradi, et al. Mapping 3Rs and NAM research and innovation projects funded through European framework programmes since 2007. Archives of Toxicology. 2026. doi:10.1007/s00204-026-04383-2
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Emmanuel Enoch Dzakah, Chao Ni, Xiaomin Feng, et al. Modernizing drug development and ensuring global equity in the organoid revolution. Communications Biology. 2026;9(1):540. doi:10.1038/s42003-026-10076-4
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Donald E. Ingber. Challenges and opportunities for human Organ Chips in FDA assessments and pharma pipelines,. Cell Stem Cell. 2026. doi:10.1016/j.stem.2025.12.022
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Matthias Eggel, Samuel Camenzind, Paulin Jirkof. Reasons to Reduce Surplus Animals in Research (in Switzerland) – Or Why the Killing and Death of Animals and Potentially Standard Husbandry Conditions Should be Classified as Harms. LEOH - Journal of Animal Law, Ethics and One Health. 2026:1-15. doi:10.58590/leoh.2026.001
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Georgia Mason, Kristine Coleman, Brenda McCowan, David Pearl, Ori Pomerantz. Ethological scars? Exposure to multiple negative events over a lifespan may predict abnormal repetitive behaviour in laboratory-housed rhesus macaques. Biology Letters. 2026;22(3):20250638. doi:10.1098/rsbl.2025.0638
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Lynn E Taylor, Etai T Bally, Zachary Burns. Supporting CDC’s Elimination of Research on Nonhuman Primates. The Journal of Infectious Diseases. 2026:jiag186. doi:10.1093/infdis/jiag186
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Federico Germani, Julian W. März, Alessandro Luciani, Olivier Devuyst, Nikola Biller-Andorno. Ethical and legal considerations of digital animal models: pioneering reduction and replacement. Trends in Biotechnology. 2026;44(3):593-595. doi:10.1016/j.tibtech.2025.08.011
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Ashley L. Eadie, Holly Fernandez Lynch, Naomi Scheinerman, Ravi B. Parikh. Advancing FDA New Approach Methodologies from animal models through digital twins. npj Digital Medicine. 2026. doi:10.1038/s41746-026-02476-x
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Michael J. Fossler, C. Edwin Garner. The FDA Roadmap to Reducing Animal Testing in Preclinical Safety Studies: Where Will It Lead Us? Clinical Pharmacology in Drug Development. 2026;15(3):e70046. doi:10.1002/cpdd.70046
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