Ethics, policy, and legislation

Ruxandra Malina Petrescu-Mag, Mathieu Vinken, Dacinia Crina Petrescu. Mapping the ethical and sustainable transition in toxicology: a bibliometric analysis and a review of new approach methodologies. Archives of Toxicology. 2025. doi:10.1007/s00204-025-04209-7

John J. Pippin, Jarrod Bailey, Mark Kennedy, et al. Institutional animal care and use committees and the challenges of evaluating animal research proposals. Research Integrity and Peer Review. 2025;10(1):11. doi:10.1186/s41073-025-00169-9

Sarah A Carratt, Christina L Zuch de Zafra, Elias Oziolor, et al. An industry perspective on the FDA Modernization Act 2.0/3.0: potential next steps for sponsors to reduce animal use in drug development. Toxicological Sciences. 2025;203(1):28-34. doi:10.1093/toxsci/kfae122

Yadvinder Bhuller, Marc Avey, Raywat Deonandan, et al. Ethical principles for regulatory risk decision-making. Regulatory Toxicology and Pharmacology. 2025:105813. doi:10.1016/j.yrtph.2025.105813

Andrew S. Robertson, Nahid Latif, Imein Bousnina, et al. Accelerating adoption of new approach methodologies in regulatory decision making: an industry perspective. Nature Reviews Drug Discovery. 2025;24(6):401-402. doi:10.1038/d41573-025-00038-6

Tessel B. Wijne, Wouter P. C. Boon, Anne S. Kienhuis, Ellen H. M. Moors, Jarno Hoekman. Pursuing societal impact in research projects on NAM development: An analysis of routes to impact. NAM Journal. 2025;1:100050. doi:10.1016/j.namjnl.2025.100050

Pandora Pound. A sociological perspective on the challenges of displacing animal research within academia: the contribution of Bourdieu. NAM Journal. 2025;1:100057. doi:10.1016/j.namjnl.2025.100057

Jessica Rosolowski, Tilo Weber, Atena Malakpour-Permlid, Stina Oredsson. Revisiting 3Rs: rethinking replacement and new approach methodologies. Frontiers in Toxicology. 2025;7. doi:10.3389/ftox.2025.1664209

Jean Knight, Costanza Rovida, Kate Willett, Jay Ingram. Fish count, too – The animal toll of REACH aquatic toxicity tests. ALTEX - Alternatives to animal experimentation. 2025. doi:10.14573/altex.2506011

Lauren Hope, Jarrod Bailey. Breaking down the barriers to animal-free research. Alternatives to Laboratory Animals. 2025;53(4):215-231. doi:10.1177/02611929251349465