Cardiovascular system

Yuhao Qiang, Abdoulaye Sissoko, Zixiang L. Liu, et al. Microfluidic study of retention and elimination of abnormal red blood cells by human spleen with implications for sickle cell disease. Proceedings of the National Academy of Sciences. 2023;120(6):e2217607120. doi:10.1073/pnas.2217607120

Justin Silberman, Jessica Boehlein, Talia Abbate, Erika Moore. A Biomaterial Model to Assess the Effects of Age in Vascularization. Cells Tissues Organs. 2023;212(1):74-83. doi:10.1159/000523859

Valeria V. Orlova, Dennis M. Nahon, Amy Cochrane, et al. Vascular defects associated with hereditary hemorrhagic telangiectasia revealed in patient-derived isogenic iPSCs in 3D vessels on chip. Stem Cell Reports. 2022;17(7):1536-1545. doi:10.1016/j.stemcr.2022.05.022

Adelaide Dura, Evangelos-Panagiotis Daskalopoulos, Laura Gribaldo, Pierre Deceuninck. EURL ECVAM Review of non-animal models in biomedical research - Cardiovascular diseases. 2022. http://data.europa.eu/89h/20947a04-86ef-473f-8907-c658e4050c24.

Justin Silberman, Aakanksha Jha, Holly Ryan, Talia Abbate, Erika Moore. Modeled vascular microenvironments: immune-endothelial cell interactions in vitro. Drug Delivery and Translational Research. 2021;11(6):2482-2495. doi:10.1007/s13346-021-00970-1

Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, et al. Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research. 2021;117(14):2742-2754. doi:10.1093/cvr/cvab088

Mosha Abulaiti, Yaxiaer Yalikun, Kozue Murata, et al. Establishment of a heart-on-a-chip microdevice based on human iPS cells for the evaluation of human heart tissue function. Scientific Reports. 2020;10(1):19201. doi:10.1038/s41598-020-76062-w

Riccardo Barrile, Andries D. van der Meer, Hyoungshin Park, et al. Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems. Clinical Pharmacology and Therapeutics. 2018;104(6):1240-1248. doi:10.1002/cpt.1054

C. G. dos Remedios, S. P. Lal, A. Li, et al. The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease. Biophysical Reviews. 2017;9(4):431-441. doi:10.1007/s12551-017-0305-3

Barry Fine, Gordana Vunjak-Novakovic. Shortcomings of Animal Models and the Rise of Engineered Human Cardiac Tissue. ACS Biomaterials Science & Engineering. 2017;3(9):1884-1897. doi:10.1021/acsbiomaterials.6b00662