Cardiovascular system

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Evangelos P Daskalopoulos, Pierre Deceuninck, Maurice Whelan, Laura Gribaldo. Transition to innovative, human-relevant pre-clinical cardiovascular research: a perspective. Cardiovascular Research. 2024:cvae080. doi:10.1093/cvr/cvae080
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Rick Xing Ze Lu, Naimeh Rafatian, Yimu Zhao, et al. Cardiac tissue model of immune-induced dysfunction reveals the role of free mitochondrial DNA and the therapeutic effects of exosomes. Science Advances. 2024;10(13):eadk0164. doi:10.1126/sciadv.adk0164
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Bettina Lickiss, Jan Hunker, Jamie Bhagwan, et al. Chamber-specific contractile responses of atrial and ventricular hiPSC-cardiomyocytes to GPCR and ion channel targeting compounds: A microphysiological system for cardiac drug development. Journal of Pharmacological and Toxicological Methods. 2024;128:107529. doi:10.1016/j.vascn.2024.107529
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Shira Landau, Yimu Zhao, Homaira Hamidzada, et al. Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms. Cell Stem Cell. 2024;31(8):1222-1238.e10. doi:10.1016/j.stem.2024.05.011
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Xuekun Wu, Kyle Swanson, Zehra Yildirim, Wenqiang Liu, Ronglih Liao, Joseph C Wu. Clinical trials in-a-dish for cardiovascular medicine. European Heart Journal. 2024;45(40):4275-4290. doi:10.1093/eurheartj/ehae519
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Dennis M. Nahon, Marc Vila Cuenca, Francijna E. van den Hil, et al. Self-assembling 3D vessel-on-chip model with hiPSC-derived astrocytes. Stem Cell Reports. 2024;19(7):946-956. doi:10.1016/j.stemcr.2024.05.006
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Huub J. Weener, Heleen H. T. Middelkamp, Andries D. van der Meer. Considering future qualification for regulatory science in the early development of microphysiological systems: a case study of microthrombosis in a Vessel-on-Chip. Frontiers in Toxicology. 2024;6. doi:10.3389/ftox.2024.1513002
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Omar Mourad, Ryan Yee, Mengyuan Li, Sara S. Nunes. Modeling Heart Diseases on a Chip: Advantages and Future Opportunities. Circulation Research. 2023;132(4):483-497. doi:10.1161/CIRCRESAHA.122.321670
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Ulgu Arslan, Marcella Brescia, Viviana Meraviglia, et al. Vascularized hiPSC-derived 3D cardiac microtissue on chip. Stem Cell Reports. 2023;18(7):1394-1404. doi:10.1016/j.stemcr.2023.06.001
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Brett Volmert, Artem Kiselev, Aniwat Juhong, et al. A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization. Nature Communications. 2023;14:8245. doi:10.1038/s41467-023-43999-1
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