Cancer

Jennifer M. Rosenbluth, Ron C. J. Schackmann, G. Kenneth Gray, et al. Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages. Nature Communications. 2020;11(1):1711. doi:10.1038/s41467-020-15548-7

Kanako Yuki, Ning Cheng, Michitaka Nakano, Calvin J. Kuo. Organoid Models of Tumor Immunology. Trends in Immunology. 2020;41(8):652-664. doi:10.1016/j.it.2020.06.010

Else Driehuis, Kai Kretzschmar, Hans Clevers. Establishment of patient-derived cancer organoids for drug-screening applications. Nature Protocols. 2020;15(10):3380-3409. doi:10.1038/s41596-020-0379-4

David Tuveson, Hans Clevers. Cancer modeling meets human organoid technology. Science (New York, N.Y.). 2019;364(6444):952-955. doi:10.1126/science.aaw6985

Jarno Drost, Hans Clevers. Organoids in cancer research. Nature Reviews. Cancer. 2018;18(7):407-418. doi:10.1038/s41568-018-0007-6

Shurong Hou, Hervé Tiriac, Banu Priya Sridharan, et al. Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening. SLAS discovery: advancing life sciences R & D. 2018;23(6):574-584. doi:10.1177/2472555218766842

James T. Neal, Xingnan Li, Junjie Zhu, et al. Organoid Modeling of the Tumor Immune Microenvironment. Cell. 2018;175(7):1972-1988.e16. doi:10.1016/j.cell.2018.11.021

Norman Sachs, Joep de Ligt, Oded Kopper, et al. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity. Cell. 2018;172(1-2):373-386.e10. doi:10.1016/j.cell.2017.11.010

Eduard Batlle, Hans Clevers. Cancer stem cells revisited. Nature Medicine. 2017;23(10):1124-1134. doi:10.1038/nm.4409

William G. Kaelin. Common pitfalls in preclinical cancer target validation. Nature Reviews. Cancer. 2017;17(7):425-440. doi:10.1038/nrc.2017.32