Aging

Guido Kroemer, Andrea B. Maier, Ana Maria Cuervo, et al. From geroscience to precision geromedicine: Understanding and managing aging. Cell. 2025;188(8):2043-2062. doi:10.1016/j.cell.2025.03.011

Cristina Dolciotti, Marco Righi, Eleonora Grecu, et al. The translational power of Alzheimer's-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history. Frontiers in Cellular Neuroscience. 2025;19. doi:10.3389/fncel.2025.1553642

Felipe Mendes Delpino, Alexandre Dias Porto Chiavegatto Filho, Juliana Lustosa Torres, Fabíola Bof de Andrade, Maria Fernanda Lima-Costa, Bruno Pereira Nunes. Predicting all-cause mortality with machine learning among Brazilians aged 50 and over: results from The Brazilian Longitudinal Study of Ageing (ELSI-Brazil). npj Aging. 2025;11(1):1-8. doi:10.1038/s41514-025-00210-7

Seungman Park, Thomas C. Laskow, Jingchun Chen, Prasun Guha, Buddhadeb Dawn, Deok-Ho Kim. Microphysiological systems for human aging research. Aging Cell. 2024;23(3):e14070. doi:10.1111/acel.14070

Abhijeet Venkataraman, Ivan Kordic, JiaXun Li, et al. Decoding senescence of aging single cells at the nexus of biomaterials, microfluidics, and spatial omics. npj Aging. 2024;10(1):1-27. doi:10.1038/s41514-024-00178-w

Patricia R. Pitrez, Luis M. Monteiro, Oliver Borgogno, Xavier Nissan, Jerome Mertens, Lino Ferreira. Cellular reprogramming as a tool to model human aging in a dish. Nature Communications. 2024;15(1):1816. doi:10.1038/s41467-024-46004-5

Leandro H. Gallo, Nesar Akanda, Kaveena Autar, et al. A functional aged human iPSC-cortical neuron model recapitulates Alzheimer’s disease, senescence, and the response to therapeutics. Alzheimer’s & Dementia. 2024;20(9):5940-5960. doi:10.1002/alz.14044

Hyo Lee, Aimee J. Aylward, Richard V. Pearse, et al. Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1. Cell Reports. 2023;42(8):112994. doi:10.1016/j.celrep.2023.112994

Jonas Cerneckis, Guojun Bu, Yanhong Shi. Pushing the boundaries of brain organoids to study Alzheimer’s disease. Trends in Molecular Medicine. 2023;29(8):659-672. doi:10.1016/j.molmed.2023.05.007

Francesca Veronesi, Deyanira Contartese, Laura Di Sarno, Veronica Borsari, Milena Fini, Gianluca Giavaresi. In Vitro Models of Cell Senescence: A Systematic Review on Musculoskeletal Tissues and Cells. International Journal of Molecular Sciences. 2023;24(21):15617. doi:10.3390/ijms242115617