%0 Journal Article %K Cell Survival %K Cells, Cultured %K Chemical and Drug Induced Liver Injury %K Coculture Techniques %K cryopreservation %K Cytochrome P-450 Enzyme System %K Dose-Response Relationship, Drug %K Hepatocytes %K Humans %K Male %K Middle Aged %K Models, Biological %K Pharmaceutical Preparations %K Predictive Value of Tests %K Primary Cell Culture %K Spheroids, Cellular %K Time Factors %K Toxicity Tests %B Toxicological Sciences: An Official Journal of the Society of Toxicology %D 2018 %G eng %N 2 %P 655-666 %R 10.1093/toxsci/kfx289 %T Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study %V 162 %8 2018-04-01 %! Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications