%0 Journal Article %K animal research %K digital animal models %K ethics %K Reduction %K replacement %B Trends in Biotechnology %D 2026 %G English %N 3 %P 593-595 %R 10.1016/j.tibtech.2025.08.011 %T Ethical and legal considerations of digital animal models: pioneering reduction and replacement %U https://www.cell.com/trends/biotechnology/abstract/S0167-7799(25)00347-6 %V 44 %8 2026-03-01 %! Ethical and legal considerations of digital animal models