%0 Journal Article %K Alzheimer’s disease %K complex in vitro models %K environmental toxicants %K gut-brain axis %K infectious hypothesis %K neuroinflammation %K organ-on-a-chip %K organoids %B Frontiers in Toxicology %D 2026 %G English %R 10.3389/ftox.2025.1753572 %T Beyond the amyloid hypothesis: leveraging human-centered complex in vitro models to decode Alzheimer’s disease etiology %U https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2025.1753572/full %V 7 %8 2026-01-09 %! Beyond the amyloid hypothesis