%0 Journal Article
%K Clinical trial
%K Drug development
%K Drug optimization
%K Structure‒tissue exposure/selectivity relationship (STR)
%K Structure‒tissue exposure/selectivity–activity relationship (STAR)
%B Acta Pharmaceutica Sinica B
%D 2022
%N 7
%P 3049-3062
%R 10.1016/j.apsb.2022.02.002
%T Why 90% of clinical drug development fails and how to improve it?
%U https://www.sciencedirect.com/science/article/pii/S2211383522000521
%V 12
%8 2022-07-01