%0 Journal Article %K AI in drug discovery %K animal alternatives %K Biomedical Research %K computational modeling %K regulatory science %K simulation models %K translational research %B Frontiers in Pharmacology %D 2025 %G English %R 10.3389/fphar.2025.1644907 %T Exploring the potential of computer simulation models in drug testing and biomedical research: a systematic review %U https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1644907/full %V 16 %8 2025-09-24 %! Exploring the potential of computer simulation models in drug testing and biomedical research