%0 Journal Article %K drug safety %K Preclinical research %B Nature Reviews Drug Discovery %D 2025 %G en %P 1-16 %R 10.1038/s41573-025-01308-z %T Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety %U https://www.nature.com/articles/s41573-025-01308-z %8 2025-10-27 %! Quantitative systems toxicology