%0 Journal Article %K 4R principles %K Animal ethics %K animal research %K ethnopharmacology %K responsibility %B Frontiers in Pharmacology %D 2025 %G English %R 10.3389/fphar.2025.1543316 %T Practical implementation and impact of the 4R principles in ethnopharmacology: Pursuing a more humane approach to research %U https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1543316/full %V 16 %8 2025-03-28 %! Practical implementation and impact of the 4R principles in ethnopharmacology