%0 Journal Article %K 3Rs %K microphysiological systems %K new approach methodologies %K Next-Generation Risk Assessment (NGRA) %K organ-on-chip %B Frontiers in Toxicology %D 2025 %G English %R 10.3389/ftox.2025.1649393 %T Alternatives to animal-derived extracellular matrix hydrogels? An explorative study with HepaRG cells in animal-free hydrogels under static and dynamic culture conditions %U https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2025.1649393/full %V 7 %8 2025-10-01 %! Alternatives to animal-derived extracellular matrix hydrogels?