TY - ECHAP
KW - biobank
KW - Biobank governance
KW - Ethical, Legal, and Social Implications (ELSI)
KW - Human tissue
KW - informed consent
AU - Victoria Corbit
AU - Azra Hasan
AU - Thomas J. Bell
AU - Melissa W. VonDran
AU - Catharine E. Krebs
AU - Gail A. Van Norman
AB - Human tissues serve as an ideal model system for expanding our understanding of human health and disease because they allow researchers to connect mechanistic findings from cell models with relevant applications in humans. Access to human biospecimens is made possible by biobanks that procure, store, and distribute samples for research. The types of samples available in biorepositories around the world vary widely in sample type, donor demographics, and preservation methods, enabling research across a range of areas. This chapter describes key information for researchers interested in conducting research with human biospecimens. We describe the following: (1) the options for obtaining human tissue for research and the different types of bioresources that exist; (2) ethical and legal requirements for human biospecimen collections and implications for biobank governance, including informed consent, and (3) innovations within biospecimen and biorepository science that are enhancing rigor, reproducibility, and the increased use of human biospecimens for research.
BT - Moving Toward Nonanimal Approaches in Medical Research and Testing
DA - 2027-01-01
N2 - Human tissues serve as an ideal model system for expanding our understanding of human health and disease because they allow researchers to connect mechanistic findings from cell models with relevant applications in humans. Access to human biospecimens is made possible by biobanks that procure, store, and distribute samples for research. The types of samples available in biorepositories around the world vary widely in sample type, donor demographics, and preservation methods, enabling research across a range of areas. This chapter describes key information for researchers interested in conducting research with human biospecimens. We describe the following: (1) the options for obtaining human tissue for research and the different types of bioresources that exist; (2) ethical and legal requirements for human biospecimen collections and implications for biobank governance, including informed consent, and (3) innovations within biospecimen and biorepository science that are enhancing rigor, reproducibility, and the increased use of human biospecimens for research.
PB - Academic Press
PY - 2027
SN - 978-0-443-26514-3
SP - 159
EP - 175
ST - Chapter 10 - Biobanks
T2 - Moving Toward Nonanimal Approaches in Medical Research and Testing
TI - Chapter 10 - Biobanks: Yielding extraordinary returns for human health and disease
UR - https://www.sciencedirect.com/science/article/pii/B9780443265143000035
Y2 - 2026-10-05
ER -