TY - JOUR
KW - Comorbidities
KW - Oncology
AU - Johnique T. Atkins
AU - Goldy C. George
AU - Kenneth Hess
AU - Kathrina L. Marcelo-Lewis
AU - Ying Yuan
AU - Gautam Borthakur
AU - Sean Khozin
AU - Patricia LoRusso
AU - David S. Hong
AB - Our objective was to determine the correlation between preclinical toxicity found in animal models (mouse, rat, dog and monkey) and clinical toxicity reported in patients participating in Phase 1 oncology clinical trials.
BT - British Journal of Cancer
DA - 2020-11
DO - 10.1038/s41416-020-01033-x
IS - 10
LA - en
N2 - Our objective was to determine the correlation between preclinical toxicity found in animal models (mouse, rat, dog and monkey) and clinical toxicity reported in patients participating in Phase 1 oncology clinical trials.
PY - 2020
SP - 1496
EP - 1501
T2 - British Journal of Cancer
TI - Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trials
UR - https://www.nature.com/articles/s41416-020-01033-x
VL - 123
Y2 - 2026-08-20
SN - 1532-1827
ER -