TY - JOUR
KW - Electrophysiology
KW - Imaging
KW - Sensors and probes
KW - Stem-cell biotechnology
KW - Tissue engineering
AU - Yoonhee Jin
AU - Seongjun Park
AU - Seung-Woo Cho
AB - 3D cell culture systems such as organoids reflect the complexity of native organs more closely than traditional 2D culture systems. However, efforts to translate organoid research into clinical and industrial applications demand the development of compatible analytical platforms to accurately characterize their multifaceted physiological traits. This Review explores three vital aspects of physiological characterization — electrophysiological, biophysical and optical properties — including the role of omics and computational technologies in understanding organoid function and behaviour.
BT - Nature Reviews Bioengineering
DA - 2026-04
DO - 10.1038/s44222-025-00384-5
IS - 4
LA - en
N2 - 3D cell culture systems such as organoids reflect the complexity of native organs more closely than traditional 2D culture systems. However, efforts to translate organoid research into clinical and industrial applications demand the development of compatible analytical platforms to accurately characterize their multifaceted physiological traits. This Review explores three vital aspects of physiological characterization — electrophysiological, biophysical and optical properties — including the role of omics and computational technologies in understanding organoid function and behaviour.
PY - 2026
SP - 336
EP - 352
T2 - Nature Reviews Bioengineering
TI - Organoid analytical toolkits
UR - https://www.nature.com/articles/s44222-025-00384-5
VL - 4
Y2 - 2026-08-12
SN - 2731-6092
ER -