TY - JOUR
KW - biomaterials
KW - Immunology
KW - Tissue engineering
AU - Joel P. Joseph
AU - Sriram Bharath Gugulothu
AU - Dipankar Nandi
AU - Kaushik Chatterjee
AB - 3D bioprinting has evolved as a promising new approach to build physiologically relevant in vitro tissue microenvironments. Recent evidence demonstrates that microenvironmental cues regulate immune cell activation and function, making bioprinted immune niches valuable for basic and translational immunology research. This review outlines key considerations for 3D bioprinting immune niches, particularly bioinks and biofabrication strategies. Drawing from bioprinted tissue constructs, immune niches, and the anatomy of the immune system, we suggest directions to expand the bioprinting toolbox for immune niches.
BT - Trends in Biotechnology
DA - 2026-05-13
DO - 10.1016/j.tibtech.2026.04.017
N2 - 3D bioprinting has evolved as a promising new approach to build physiologically relevant in vitro tissue microenvironments. Recent evidence demonstrates that microenvironmental cues regulate immune cell activation and function, making bioprinted immune niches valuable for basic and translational immunology research. This review outlines key considerations for 3D bioprinting immune niches, particularly bioinks and biofabrication strategies. Drawing from bioprinted tissue constructs, immune niches, and the anatomy of the immune system, we suggest directions to expand the bioprinting toolbox for immune niches.
PY - 2026
ST - Next-generation immune models
T2 - Trends in Biotechnology
TI - Next-generation immune models: bioinks, 3D bioprinting, and future directions
UR - https://www.sciencedirect.com/science/article/pii/S0167779926001526
Y2 - 2026-05-18
SN - 0167-7799
ER -