TY - JOUR
KW - Allogregnanolone
KW - Alzheimer’s disease
KW - Estrogen
KW - Fetal microchimerism
KW - Immune
KW - Maternal
KW - multiple sclerosis
KW - Postpartum depression
KW - Progesterone
KW - Prolactin
KW - Stroke
AU - Nicholas P. Deems
AU - Benedetta Leuner
AB - Risk and resilience in brain health and disease can be influenced by a variety of factors. While there is a growing appreciation to consider sex as one of these factors, far less attention has been paid to sex-specific variables that may differentially impact females such as pregnancy and reproductive history. In this review, we focus on nervous system disorders which show a female bias and for which there is data from basic research and clinical studies pointing to modification in disease risk and progression during pregnancy, postpartum and/or as a result of parity: multiple sclerosis (MS), depression, stroke, and Alzheimer’s disease (AD). In doing so, we join others (Shors, 2016; Galea et al., 2018a) in aiming to illustrate the importance of looking beyond sex in neuroscience research.
BT - Frontiers in Neuroendocrinology
DA - 2020-04-01
DO - 10.1016/j.yfrne.2020.100820
N2 - Risk and resilience in brain health and disease can be influenced by a variety of factors. While there is a growing appreciation to consider sex as one of these factors, far less attention has been paid to sex-specific variables that may differentially impact females such as pregnancy and reproductive history. In this review, we focus on nervous system disorders which show a female bias and for which there is data from basic research and clinical studies pointing to modification in disease risk and progression during pregnancy, postpartum and/or as a result of parity: multiple sclerosis (MS), depression, stroke, and Alzheimer’s disease (AD). In doing so, we join others (Shors, 2016; Galea et al., 2018a) in aiming to illustrate the importance of looking beyond sex in neuroscience research.
PY - 2020
EP - 100820
ST - Pregnancy, postpartum and parity
T2 - Frontiers in Neuroendocrinology
TI - Pregnancy, postpartum and parity: Resilience and vulnerability in brain health and disease
UR - https://www.sciencedirect.com/science/article/pii/S0091302220300017
VL - 57
Y2 - 2026-02-24
SN - 0091-3022
ER -