TY - JOUR KW - AI KW - Explainable AI KW - FAIR data KW - Hazard and risk assessment KW - Toxicology KW - Trust AU - Timothy W. Gant AU - Alistair Boxall AU - Daniel Burgwinkel AU - Maryam Zare Jeddi AU - Ivo Djidrovski AU - Steffi Friedrichs AU - Barry Hardy AU - Thomas Hartung AU - Daniela Holland AU - Andreas Karwath AU - Anne Kienhuis AU - Nicole Kleinstreuer AU - Zhoumeng Lin AU - Emma L. Marczylo AU - Antonino Marvuglia AU - Hua Qian AU - Bennard van Ravenzwaay AU - Paul Rees AU - Haralambos Sarimveis AU - Tewes Tralau AU - Lucy Wilmot AU - Adam Zalewski AU - David RouquiƩ AB - Artificial Intelligence (AI) is increasingly influencing chemical risk assessment, enabling faster, more comprehensive, and potentially more ethical assessments. The application of AI in chemical risk assessment refers to both generative and predictive algorithms encompassing machine learning, to analyse complex chemical, biological, and environmental data and provide insights into adverse effect potential for humans and ecosystems. AI systems support the prediction of chemical hazards, exposure levels, and adverse effects by learning from experimental results, mechanistic models, and regulatory datasets, thereby enhancing the efficiency of safety evaluations. BT - Archives of Toxicology DA - 2026-02-17 DO - 10.1007/s00204-025-04286-8 LA - en N2 - Artificial Intelligence (AI) is increasingly influencing chemical risk assessment, enabling faster, more comprehensive, and potentially more ethical assessments. The application of AI in chemical risk assessment refers to both generative and predictive algorithms encompassing machine learning, to analyse complex chemical, biological, and environmental data and provide insights into adverse effect potential for humans and ecosystems. AI systems support the prediction of chemical hazards, exposure levels, and adverse effects by learning from experimental results, mechanistic models, and regulatory datasets, thereby enhancing the efficiency of safety evaluations. PY - 2026 ST - Building trust in the integration of artificial intelligence into chemical risk assessment T2 - Archives of Toxicology TI - Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop UR - https://doi.org/10.1007/s00204-025-04286-8 Y2 - 2026-02-23 SN - 1432-0738 ER -