TY - JOUR KW - Biological techniques KW - Biotechnology KW - Engineering KW - medical research KW - Stem cells AU - Dohui Kim AU - Jaeseung Youn AU - Juhyeok Kim AU - Jeongmin Lee AU - Jangwon Yoon AU - Dong Sung Kim AB - In this review, we systematically categorize diverse organoid engineering strategies—including cellular programming, material engineering, and platform- or system-level innovations—according to their impact on reproducibility and scalability, and highlight representative applications and emerging directions. By reframing organoid generation as a manufacturing process, these technological advances pave the way toward standardized and high-fidelity organoid production for both fundamental research and translational applications. BT - npj Biomedical Innovations DA - 2026-02-02 DO - 10.1038/s44385-025-00054-6 IS - 1 LA - en N2 - In this review, we systematically categorize diverse organoid engineering strategies—including cellular programming, material engineering, and platform- or system-level innovations—according to their impact on reproducibility and scalability, and highlight representative applications and emerging directions. By reframing organoid generation as a manufacturing process, these technological advances pave the way toward standardized and high-fidelity organoid production for both fundamental research and translational applications. PY - 2026 EP - 12 ST - From organoid culture to manufacturing T2 - npj Biomedical Innovations TI - From organoid culture to manufacturing: technologies for reproducible and scalable organoid production UR - https://www.nature.com/articles/s44385-025-00054-6 VL - 3 Y2 - 2026-02-02 SN - 3005-1444 ER -