01686nas a2200229   4500000000100000008004100001260003100042653000900073653001600082653002400098653002000122653002600142100002200168700002300190700002300213700002300236245009800259856007500357300001200432520099000444020002201434       2027                            d  c2027-01-01bAcademic Press10abias10apeer review10aResearch assessment10aResearch grants10aScientific publishing1 aEmily R. Trunnell1 aCatharine E. Krebs1 aCatharine E. Krebs1 aGail A. Van Norman00aChapter 15 - Overcoming animal methods bias and its impacts on nonanimal research assessments  uhttps://www.sciencedirect.com/science/article/pii/B9780443265143000126  a243-2583 aAs awareness, acceptance, and use of nonanimal research methods grow, critical barriers to their full adoption remain. One of these barriers is animal methods bias—a preference for animal-based methods or lack of expertise to adequately evaluate nonanimal methods, resulting in unfair assessments of nonanimal research. In this chapter, we explore the evidence for animal methods bias in research assessment and the historical and systemic factors contributing to it, including the structural incentives that drive the research ecosystem. Mitigation recommendations for researchers, funders, and publishers are provided, adapted from work by the Coalition to Illuminate and Address Animal Methods Bias, and research gaps in understanding and correcting this bias are identified. Additional research and advocacy on animal methods bias are needed to understand its full impact on the uptake and acceptance of nonanimal methods and the persistence of animal use in biomedical research.  a978-0-443-26514-3