00562nas a2200097   4500000000100000000000100001008004100002245010200043856005600145520026300201                                       d00aTargeting an atypical G protein–coupled receptor signaling pathway for cardiac fibrosis therapy  uhttps://www.science.org/doi/10.1126/science.aej58963 aCardiac fibrosis independently predicts adverse outcomes in heart failure (HF), yet no Food and Drug Administration–approved therapy directly targets fibrotic remodeling in the heart. To address this unmet clinical need, we used a multidimensional drug ...