00508nas a2200097   4500000000100000000000100001008004100002245008800043856013300131520014600264                                       d00aIt Is Time To Require Human-Relevant Efficacy Evidence Before First-In-Human Trials  uhttps://www.drugdiscoveryonline.com/doc/it-is-time-to-require-human-relevant-efficacy-evidence-before-first-in-human-trials-00013 aWhy, when human-relevant evidence of likely efficacy can be generated before a trial begins, is it not evaluated before patients are exposed?