01437nas a2200505   4500000000100000008004100001260001500042653003200057653002600089653002000115653003100135653002200166653002100188100002000209700001600229700002100245700002000266700002300286700001700309700002100326700002100347700001700368700001700385700002500402700002100427700002000448700001900468700001900487700002200506700001400528700002200542700002100564700002500585700002100610700002000631700002300651700001900674700001800693245010800711856007200819300001100891490000600902520000900908022001400917       2026                            d  c2026-01-0110aDrivers of system behaviour10aEffective use of NAMs10aSystem dynamics10aSystem-level interventions10aSystems modelling10aSystems thinking1 aGro H. Mathisen1 aPaul Whaley1 aBirgit Kopainsky1 aHeather M. Ames1 aSebastian Hoffmann1 aTrine Husøy1 aLowenna B. Jones1 aCamilla Svendsen1 aGunn E. Vist1 aDenise Bloch1 aAleksandra Čavoški1 aWeihsueh A. Chiu1 aHolly G. Davies1 aArianna Giusti1 aThomas Hartung1 aHelena T. Hogberg1 aSeok Kwon1 aOlivia J. Osborne1 aAndrew A. Rooney1 aChristophe Rousselle1 aJennifer B. Sass1 aUlla Simanainen1 aKristina A. Thayer1 aDaniele Wikoff1 aAngela Bearth00aPreparing for CHANGE: How systems thinking supports an effective transition from animal studies to NAMs  uhttps://www.sciencedirect.com/science/article/pii/S3050620426000436  a1001180 v23 aNone  a3050-6204