00713nas a2200133 4500000000100000000000100001008004100002260001500043100002900058245010500087856004700192520032600239022001400565 2026 d c2026-05-161 aBenjamin Victor Ineichen00aWe need less animal research, better animal research, and animal research done for the right reasons uhttps://doi.org/10.1186/s12967-026-08259-y3 aAnimal research has contributed to modern medicine and continues to play an important role in biomedical science. At the same time, its scale and quality deserve closer scrutiny. If it is to retain scientific and societal legitimacy, we must be clear about when we use it, how we conduct it, and why we rely on it at all. a1479-5876