02481nas a2200325   4500000000100000008004100001260001500042653001800057653001100075653001400086653001400100653001500114100001800129700001800147700001900165700001700184700002000201700002300221700001800244700002000262700001900282700002000301700002700321245008400348856007200432300001000504490000700514520162000521022001402141       2022                            d  c2022-12-0110aBreast cancer10aGlobal10aIncidence10aMortality10aPrediction1 aMelina Arnold1 aEileen Morgan1 aHarriet Rumgay1 aAllini Mafra1 aDeependra Singh1 aMathieu Laversanne1 aJerome Vignat1 aJulie R. Gralow1 aFatima Cardoso1 aSabine Siesling1 aIsabelle Soerjomataram00aCurrent and future burden of breast cancer: Global statistics for 2020 and 2040  uhttps://www.sciencedirect.com/science/article/pii/S0960977622001448  a15-230 v663 aBackground
Breast cancer is the most commonly diagnosed cancer worldwide, and its burden has been rising over the past decades. In this article, we examine and describe the global burden of breast cancer in 2020 and predictions for the year 2040.
Methods
Estimates of new female breast cancer cases and deaths in 2020 were abstracted from the GLOBOCAN database. Age-standardized incidence and mortality rates were calculated per 100,000 females by country, world region, and level of human development. Predicted cases and deaths were computed based on global demographic projections for the year 2040.
Results
Over 2.3 million new cases and 685,000 deaths from breast cancer occurred in 2020. Large geographic variation across countries and world regions exists, with incidence rates ranging from <40 per 100,000 females in some Asian and African countries, to over 80 per 100,000 in Australia/New Zealand, Northern America, and parts of Europe. Smaller geographical variation was observed for mortality; however, transitioning countries continue to carry a disproportionate share of breast cancer deaths relative to transitioned countries. By 2040, the burden from breast cancer is predicted to increase to over 3 million new cases and 1 million deaths every year because of population growth and ageing alone.
Conclusion
Breast cancer is the most common cancer worldwide and continues to have a large impact on the global number of cancer deaths. Global efforts are needed to counteract its growing burden, especially in transitioning countries where incidence is rising rapidly, and mortality rates remain high.  a0960-9776