01570nas a2200169   4500000000100000000000100001008004100002260001500043100001800058700002500076245008100101856003800182300001200220490000700232520114700239022001401386       2015                            d  c2015-07-011 aAngena Agenor1 aSohinee Bhattacharya00aInfertility and Miscarriage: Common Pathways in Manifestation and Management  uhttps://doi.org/10.2217/WHE.15.19  a527-5410 v113 aThe relationship between miscarriage and fertility is complex. While most healthcare settings treat miscarriage as a problem of subfertility in assisted reproduction units, others believe that miscarriage occurs in super-fertile women. Infertile women undergoing assisted reproduction are at a greater risk of having a miscarriage especially at an advanced age compared with women conceiving naturally. Aberrant expression of immunological factors and chromosomal abnormalities underlie both infertility and miscarriage. Common risk factors include increased maternal age, obesity, smoking, alcohol, pre-existing medical conditions and anatomical abnormalities of the reproductive system. Management pathways of both conditions may be similar with pre-implantation genetic testing and assisted reproductive technology used in both conditions. This paper discusses the synergies and differences between the two conditions in terms of their epidemiology, etiopathogenesis, risk factors and management strategies. The two conditions are related as degrees of severity of reproductive failure with common pathways in manifestation and management.  a1745-5057