00506nas a2200157 4500000000100000008004100001260001500042100002800057700002100085700002100106700002400127245012200151856005300273300001600326490000600342 2025 d c2025-12-241 aRicardo Scheufen Tieghi1 aTracy Beth Høeg1 aMartin A. Makary1 aNicole Kleinstreuer00aThe Promise of Animal Testing Alternatives at the U.S. Food and Drug Administration and National Institutes of Health uhttps://ai.nejm.org/doi/full/10.1056/AIpc2500587 aAIpc25005870 v3