@inbook{bibcite_9361, keywords = {biobank, Biobank governance, Ethical, Legal, and Social Implications (ELSI), Human tissue, informed consent}, author = {Victoria Corbit and Azra Hasan and Thomas J. Bell and Melissa W. VonDran}, editor = {Catharine E. Krebs and Gail A. Van Norman}, title = {Chapter 10 - Biobanks: Yielding extraordinary returns for human health and disease}, abstract = {Human tissues serve as an ideal model system for expanding our understanding of human health and disease because they allow researchers to connect mechanistic findings from cell models with relevant applications in humans. Access to human biospecimens is made possible by biobanks that procure, store, and distribute samples for research. The types of samples available in biorepositories around the world vary widely in sample type, donor demographics, and preservation methods, enabling research across a range of areas. This chapter describes key information for researchers interested in conducting research with human biospecimens. We describe the following: (1) the options for obtaining human tissue for research and the different types of bioresources that exist; (2) ethical and legal requirements for human biospecimen collections and implications for biobank governance, including informed consent, and (3) innovations within biospecimen and biorepository science that are enhancing rigor, reproducibility, and the increased use of human biospecimens for research.}, year = {2027}, journal = {Moving Toward Nonanimal Approaches in Medical Research and Testing}, pages = {159-175}, month = {2027-01-01}, publisher = {Academic Press}, isbn = {978-0-443-26514-3}, url = {https://www.sciencedirect.com/science/article/pii/B9780443265143000035}, }