@article{bibcite_9056, keywords = {Comorbidities, Oncology}, author = {Johnique T. Atkins and Goldy C. George and Kenneth Hess and Kathrina L. Marcelo-Lewis and Ying Yuan and Gautam Borthakur and Sean Khozin and Patricia LoRusso and David S. Hong}, title = {Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trials}, abstract = {Our objective was to determine the correlation between preclinical toxicity found in animal models (mouse, rat, dog and monkey) and clinical toxicity reported in patients participating in Phase 1 oncology clinical trials.}, year = {2020}, journal = {British Journal of Cancer}, volume = {123}, pages = {1496-1501}, month = {2020-11}, issn = {1532-1827}, url = {https://www.nature.com/articles/s41416-020-01033-x}, doi = {10.1038/s41416-020-01033-x}, language = {en}, }