@article{bibcite_8876, keywords = {Biomaterials {\textendash} cells, Biomedical Engineering, Mechanical engineering, Tissue engineering}, author = {Chao-Fan He and Tian-Hong Qiao and Guang-Hao Wang and Yuan Sun and Yong He}, title = {High-resolution projection-based 3D bioprinting}, abstract = {Projection-based 3D printing is a vat polymerization printing method that works by generating bitmaps as dynamic masks to project onto a photosensitive material surface for layer-by-layer curing. Projection-based 3D printing has the highest resolution/time for manufacturing ratio among all 3D printing technologies; however, projection-based 3D bioprinting, which uses bioinks as printing materials that contain cells and/or biomolecules, suffers from low printing resolution, with a substantial gap between the theoretical and the actual resolution. In this Review, we summarize the steps and challenges to achieve high-resolution projection-based 3D bioprinting and provide pragmatic optimization strategies for tissue engineering and regenerative medicine applications.}, year = {2025}, journal = {Nature Reviews Bioengineering}, volume = {3}, pages = {143-158}, month = {2025-02}, issn = {2731-6092}, url = {https://www.nature.com/articles/s44222-024-00218-w}, doi = {10.1038/s44222-024-00218-w}, language = {en}, }