@article{bibcite_8226,
  author = {Gautam Mahajan and Erin Doherty and Tania To and Arlene Sutherland and Jennifer Grant and Abidemi Junaid and Aakanksha Gulati and Nina LoGrande and Zohreh Izadifar and Sanjay Sharma Timilsina and Viktor Horvath and Roberto Plebani and Michael France and Indriati Hood-Pishchany and Seth Rakoff-Nahoum and Douglas S. Kwon and Girija Goyal and Rachelle Prantil-Baun and Jacques Ravel and Donald E. Ingber},
  title = {Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip},
  abstract = {A dominance of non-iners Lactobacillus species in the vaginal microbiome is optimal and strongly associated with gynecological and obstetric health, while the presence of diverse obligate or facultative anaerobic bacteria and a paucity in Lactobacillus species, similar to communities found in bacterial vaginosis (BV), is considered non-optimal and associated with adverse health outcomes. Various therapeutic strategies are being explored to modulate the composition of the vaginal microbiome; however, there is no human model that faithfully reproduces the vaginal epithelial microenvironment for preclinical validation of potential therapeutics or testing hypotheses about vaginal epithelium-microbiome interactions.},
  year = {2022},
  journal = {Microbiome},
  volume = {10},
  pages = {201},
  month = {2022-11-26},
  issn = {2049-2618},
  url = {https://doi.org/10.1186/s40168-022-01400-1},
  doi = {10.1186/s40168-022-01400-1},
  language = {en},
}