@article{bibcite_7286,
  author = {ISoOR Insight Team},
  title = {Major Shift in U.S. Research Policy: CDC to End All Nonhuman Primate Experiments by 31 December 2025},
  abstract = {On 21 November 2025, the U.S. Centers for Disease Control and Prevention (CDC) received an internal directive from ~the Department of Health and Human Services (HHS) ordering the complete termination of all in-house research ~involving nonhuman primates {\textemdash} approximately 200 macaques {\textemdash} by the end of the calendar year. This is the first time ~since the NIH chimpanzee retirement in 2015 that a major federal agency has fully shuttered an active, ~government-owned NHP colony. The decision, driven by persistent primate shortages, documented biosafety ~incidents, translational failures of NHP models, and the accelerating maturity of human-relevant alternatives ~(organoids, microphysiological systems, organ-on-chip platforms, and AIintegrated digital twins), constitutes one ~of the most far-reaching policy realignments in U.S. biomedical research since the Animal Welfare Act of 1966 and ~the FDA Modernization Act 2.0 of 2023. This Industry News analysis places the CDC directive in full scientific, ethical, ~and regulatory context, evaluates the evidence base, addresses remaining challenges, and explores the ~transformative opportunities this shift creates for the organoid and bioscience sectors.},
  year = {2025},
  journal = {Journal of Organoid and Bioscience},
  volume = {3},
  month = {2025},
  issn = {3029-2271},
  url = {https://jobs.isoor.org/index.php/journal/article/view/60},
  language = {en},
}