@article{6476,
  keywords = {AI, Biomedical Research, Funding programme, Innovative approaches, Methods, NAMs, Patients, prevention, Public Health, regulatory acceptance, translational research, Unmet medical needs},
  author = {Francesca Pistollato and Fabia Furtmann and Sarah Abitbol and Marta Agostinho and Toni Andreu and Bianca Baluta and Regina G. H. Beets-Tan and Sonja Beken and Silvia Ciotti and Sandra Coecke and Tiago Correia and Christian Desaintes and Frédéric Destrebecq and Philippe Detilleux and Sergio Di Virgilio and Antigoni Effraimidou and Luisa Ferreira Bastos and Annalisa Gastaldello and Jens K. Habermann and Ioan Hanes and Mihajlo Jakovljevic and Hugh Laverty and Benoit Maisonneuve and Lindsay J Marshall and Dania Movia and Giorgia Pallocca and Francesco Pappalardo and Roberta Pastorino and Vilma Radvilaite and Kirsty Reid and Silke Riegger and Giulia Russo and Daniela Salvatori and Valerie Speirs and Marco Straccia and Danilo A Tagle and Jan Turner and Janny van den Eijnden–van Raaij and Laura Viviani and Helder Constantino},
  title = {Leveraging innovative research tools to meet public health challenges: a BioMed21 workshop report},
  abstract = {The biomedical research landscape is undergoing a transformative shift towards human-centric, interdisciplinary approaches aimed to enhance translational relevance, amplify research impact, and address pressing public health challenges and unmet medical needs (UMNs). Recent European and international ikenitiatives have prioritised the development and implementation of human-centric non-animal methods (NAMs) to increase research translatability, and complement or replace the use of animals in life sciences. Effective cross-sector dialogue among interest-holders is key to align goals, harmonise strategies, and cross-fertilise ideas, ensuring evidence-driven policies that deliver tangible benefits for public health and society. In this spirit, on November 18, 2024, Humane Society International/Europe (since February 14th 2025, Humane World for Animals), on behalf of the Biomedical Research for the 21st Century (BioMed21) Collaboration, hosted a science policy workshop entitled “Leveraging Innovative Research Tools to Meet Public Health Challenges”. This event provided a platform for dialogue among key interest-holders to identify priority areas requiring multidisciplinary interventions. Discussions addressed leveraging innovative technologies to tackle UMNs, reassessing research infrastructure for their future-proof potential, and advancing human-centric tools to drive transformative policy changes. Themes included the societal impact of funded research, standardisation needs, and systems-based solutions to interconnected challenges. This report summarises insights and outputs from the workshop, offering a roadmap to foster impactful, science-driven, and health-focused biomedical research paradigms that meet evolving societal and public health needs.},
  year = {2025},
  journal = {NAM Journal},
  volume = {1},
  pages = {100023},
  month = {2025-01-01},
  issn = {3050-6204},
  url = {https://www.sciencedirect.com/science/article/pii/S3050620425000181},
  doi = {10.1016/j.namjnl.2025.100023},
}