@article{5921,
  author = {Shabnam Ghiasvand and Dayananda Siddappa Thimmanahalli and Caroline Morel and Peter Piepenhagen and Dinesh Bangari},
  title = {Advanced Microscopy Techniques for Imaging New Alternative Methods},
  abstract = {Organoids, air-liquid-interface cultures, and microfluidic culture systems are only a few examples of new alternative methods (or new approach methods; NAMs) that have become an increasingly important tool for biopharmaceutical research. Both as a tool for studying disease mechanisms and as a platform for testing novel therapeutics NAMs represent a paradigm shift in translational in-vitro models and offer improved reproducibility and human translatability relative to animal models and simpler cell-based systems. The increasing adoption of NAMs also aligns with FDA Modernization Act 3.0 and increased implementation of the 3Rs principle (Replacement, Reduction, and Refinement) in animal research.},
  year = {2025},
  journal = {Microscopy and Microanalysis},
  volume = {31},
  pages = {ozaf048.449},
  month = {2025-07-01},
  issn = {1431-9276},
  url = {https://doi.org/10.1093/mam/ozaf048.449},
  doi = {10.1093/mam/ozaf048.449},
}